Lab Test: Cyanide (Blood) Level
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- Measurement of cyanide level in blood or serum following intentional or inadvertent exposure
- Smokers:
- Serum: 0.006 mg/L (0.23 micromol/L)
- Blood (fluoride/oxalate): 0.041 mg/L (1.57 micromol/L)
- Nonsmokers:
- Serum: 0.004 mg/L (0.15 micromol/L)
- Blood (fluoride/oxalate): 0.016 mg/L (0.61 micromol/L)
- Nitroprusside therapy:
- Serum: 0.01-0.06 mg/L (0.38-2.3 micromol/L)
- Blood (fluoride/oxalate): 0.05-0.5 mg/L (1.92-19.2 micromol/L)
- Suspected cyanide toxicity in smoke inhalation victims - cyanide levels of 1 mcg/mL (38.5 micromol/L) or greater are typically associated with significant symptoms. The length of exposure to carbon monoxide does not always correlate with a specific cyanide level.
- Suspected cyanide exposure or poisoning - elevated blood cyanide levels may confirm the diagnosis of cyanide poisoning but are not always clinically use3ful unless results are rap-idly available. Treatment should be initiated based on clinical presentation and index of suspicion.
- Whole blood cyanide levels and associated symptoms:
- 0.5-1 mcg/mL (20-38 micromol/L): tachycardia, flushing
- 1-2.5 mcg/mL (48-95 micromol/L): depressed level of consciousness
- 2.5-3 mcg/mL (95-114 micromol/L): coma, respiratory depression >3 mcg/mL (>114 micromol/L): death
Description
Reference Range
Indications & Uses
MESH Terms & Keywords
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